Tatiana Globus

Visiting Research Associate Professor

Contact
Thornton Hall - E222
351 McCormick Road
PO Box 400743
Charlottesville, VA 22904-1000

Phone: (434) 924-6090
FAX: (434) 924-8818
Email: tg9a@virginia.edu

Home Page:
http://www.ee.virginia.edu/profile.php?ID=40

Summary:
Tatiana Globus specializes in optical and electrical characterization and optimization of electronic and photonic materials and devices including uncooled photodetectors, photovoltaics and light-emitting diodes for the mid-infrared, and the development of infrared and terahertz (THz) sensors for environmental and medical applications. Her research interests encompass optical and terahertz spectroscopy of biological macromolecules, thin film electronic materials and structures; the investigation of density of localized states and degradation phenomena in amorphous and polycrystalline silicon thin film transistors and photovoltaics. One of her main achievements is development of optical interference spectroscopy technique to characterize thin films and multilayer structures, spectroscopy of electronic defects.

Dr. Globus is among pioneers in research on terahertz/bio interactions, and her efforts are helping to open a new and very fruitful field of THz vibrational resonance spectroscopy of biological and artificial macromolecules and species. Many of the initial successful measurements of the THz resonance absorption of biological and organic materials have been performed at the University of Virginia. Dr. T. Globus is using a well resolved vibrational spectroscopy of biological and explosive materials in the spectral range of 100 GHz and higher (for biomolecules) or 0.2-3 THz (for explosives).

In parallel with experimental characterization, Dr Globus is involved in developing computational modeling technique to simulate THz spectroscopic signature of large macromolecules of DNA, RNA, proteins and other molecular components of bacterial cells using the energy minimization, normal mode analysis and molecular dynamics (MD) approaches.

During last years, the research interests of Dr. Globus are shifting in the direction of THz biosensing technology for environmental and medical applications and she is currently involved in developing Spectroscopic Imaging Technology for THz Biosensors with objectives to develop an all optical, appertureless, THz transmission instrument with the spatial resolution below the diffraction limit. The new proposed process for coupling between THz radiation and biomaterials allows for dramatic improvements in sensitivity, reliability, and selectivity of terahertz detection systems.

Background:
Tatiana Globus received her M.S. degree in Electrical Engineering from the Moscow Institute of Energy and Ph.D. degree from the Research Institute of Applied Physics (Moscow) in 1965 and 1973, respectively. Dr. Globus has served on the faculty at UVA since 1993. She has published more than 50 technical articles and presentations. She holds 3 patents for optoelectronic device technology.

Research

  • DTRA project,May 2008-May 2011, "New Molecular Recognition Signatures in the EM Spectrum". ARO, April 2008, "Terahertz Science & Technology: Sensing Bio-Molecular Nanostructures & Photoinduces Transitions Between Metastable States" (ARO).
  • ARO, SBIR Phase I and II, June 2007-June 2010, "Spectroscopic Imaging Technology for THz Bio-Sensor integrated with a Lab-on-a Chip Platform"
  • DTRA project,February 2005, "New Concepts for Detection Biological Targets: Terahertz Signature Data Base Generation".
  • NSF, 1999, "Submillimeter Wave Characterization of DNA Macromolecules". ARO MURI, 2001, "Science and Technology of Biological and Chemical Sensing", Co-PI, PI for the Scientific Task:Terahertz Wave Interaction with Biological Macromolecules. This task is focused on combined experimental and theoretical spectroscopy of biological macromolecules,including nucleic acids and proteins, in Submillimeter and Millimeter Wave range with the goal to understand physical mechanisms of interactions between radiation and macromolecules. Period Covered: 06/2001-05/2006.
  • MURI Addendum, "Confirmation of Submillimeter wave Signature of Bio-Molecules by Independent Characterization Techniques" Co-PI. Period Covered: 08/01//2002 -12/31/2005.

Most Recent Publications:

  • X. Li, T. Globus, B. Gelmont, L. C. Salay, and A. Bykhovski, "Terahertz Absorption of DNA Decamer Duplex", J. Phys. Chem. A, 2008, 112 (47), 12090-12096.
  • T. Globus, A. Bykhovski, T. Khromova, B. Gelmont, L. K. Tamm, and L. C. Salay, "Low-terahertz spectroscopy of liquid water", Proc. SPIE 6772, 67720S (2007).
  • R. Parthasarathy, A. Bykhovski, Boris Gelmont, T. Globus, N. Swami, D. Woolard, "Enhanced coupling of subterahertz radiation with semiconductor periodic slot arrays", Phys. Rev. Lett., 98 (15), 153906 (2007).
  • T. Globus, D.Woolard, T.W.Crowe, T. Khromova, B. Gelmont, J. Hessler, "Terahertz Fourier transform characterization of biological materials in a liquid phase", J. Phys. D: Appl. Phys. 39 (2006) 3405-3413.
  • B. Gelmont, R. Parthasarathy, T. Globus, A. Bykhovski, and N. Swami, "Terahertz (THz) Electromagnetic Field Enhancement in Periodic Subwavelength Structures", Nanoelectronic Devices for Defense & Security (NANO-DDS) Conference, 2007.